Leucovorin Calcium Injections

Leucovorin Calcium Injections Specification

Origin
India

Dosage Form
Injection

Salt Composition
Leucovorin Calcium

Ingredients
Leucovorin Calcium, Water for Injection

Application
Hospital, Clinic

Ph Level
6.0 to 8.5

Physical Color/Texture
Clear, colorless solution

Fermentation Smell
Odorless

Storage Instructions
Store below 25C (77F), protect from light

Shelf Life
2 years

Usage
To reduce toxic effects of folic acid antagonists

Prescription Status
Prescription only

Administration Route
Intravenous / Intramuscular

Strength
50 mg/5 ml

Packing Size
5 ml vial

Compatibility
Check compatibility before mixing with other solutions

About Leucovorin Calcium Injections

Leucovorin Calcium inj:-

Leucovorin is a medication that acts the same way in the body as folic acid. Leucovorin is used to reduce the folic-acid-lowering side effects of methotrexate because it is not affected by methotrexate in the same way that folic acid is. Leucovorin is also used in combination with fluorouracil to treat cancer of the colon.

It is also used to treat a condition known as megaloblastic anemia, which is an anemia that can be caused by sprue (a condition resulting from reduced absorption of nutrients from the stomach into the bloodstream) and can occur during pregnancy and infancy.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

When used in combination with fluorouracil for colon cancer, leucovorin is injected into a vein through a specially prepared site on your skin. In this case, leucovorin is always given under the supervision of a doctor familiar with the use of cancer chemotherapy. It is always given under the supervision of a doctor in a hospital or similar setting with access to sterile equipment for preparation.

The recommended dose for this treatment depends on body size. The treatment is often given once a day for 5 days, just before injection with fluorouracil. This treatment can be repeated every 28 days, depending on response to the therapy.

Advanced Protection for Chemotherapy Patients

Leucovorin Calcium Injection is crucial in clinical oncology as it reduces the harmful effects of chemotherapy agents, such as methotrexate. It acts as a chemoprotectant, allowing for effective treatment while safeguarding healthy cells. This solution, clear and colorless, is designed for easy integration into hospital and clinic protocols.

Precise Formulation and Storage Requirements

This injection combines Leucovorin Calcium, water for injection, and other carefully selected ingredients, ensuring stability and potency. With a pH between 6.0 and 8.5 and shelf life of 2 years, it remains reliable when stored below 25C (77F) and protected from light. Such stability guarantees optimal therapeutic results whenever needed.

FAQs of Leucovorin Calcium Injections:

Q: How is Leucovorin Calcium Injection administered?

A: Leucovorin Calcium Injection is given either intravenously (IV) or intramuscularly (IM), depending on the physicians instructions and the clinical situation. It should always be administered by a qualified healthcare professional in a hospital or clinical setting.

Q: What are the primary uses of Leucovorin Calcium Injection?

A: This medication is mainly used to diminish the toxic effects of folic acid antagonists, such as methotrexate, during chemotherapy. It helps protect healthy cells from damage while allowing these potent drugs to target cancerous cells more effectively.

Q: When should compatibility be checked before administering Leucovorin Calcium Injection?

A: Compatibility must be evaluated every time you intend to mix Leucovorin Calcium Injection with other solutions or medications. This ensures there are no adverse reactions that could compromise patient safety or medication efficacy.

Q: Where should Leucovorin Calcium Injection be stored?

A: Leucovorin Calcium Injection should be stored below 25C (77F) and protected from light to maintain its shelf life and effectiveness. Follow all storage guidelines provided by the manufacturer and healthcare authorities.

Q: What are the benefits of using Leucovorin Calcium Injection during chemotherapy?

A: The key benefit is its ability to rescue healthy, non-cancerous cells from the harmful effects of certain chemotherapy agents. This reduces side effects and helps patients tolerate chemotherapy better, often allowing for higher or more effective dosing regimens.

Q: What are the main ingredients in Leucovorin Calcium Injection?

A: The main ingredients include Leucovorin Calcium, water for injection, and other pharmaceutical-grade excipients. The solution is clear, colorless, and odorless, specifically formulated for hospital and clinic use.

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