Gemzar Injection

Gemzar Injection Specification

Dosage Form
Injection

Salt Composition
Gemcitabine Hydrochloride

Origin
Pharmaceutical

Ingredients
Each vial contains Gemcitabine Hydrochloride as active ingredient, with excipients

Fermentation Smell
Odorless

Storage Instructions
Store below 30°C, protect from light

Shelf Life
24 months

Marketed By
Eli Lilly and Company India Pvt. Ltd.

Packaging Size
200 mg or 1 g vial

Compatibility
Compatible with normal saline (0.9% sodium chloride) for IV infusion

Reconstitution
Requires reconstitution with suitable sterile diluent prior to administration

Brand Name
Gemzar

Contraindications
Hypersensitivity to gemcitabine or any component of the formulation

Route of Administration
Intravenous infusion

Prescription/Non Prescription
Prescription only

Gemzar Injection Trade Information

Supply Ability
1000 Units Per Week

Delivery Time
1 Week

About Gemzar Injection

Gemzar is a nucleoside analog utilized as chemotherapy. It is promoted as Gemzar by Eli Lilly and Company.

Complete Description:

Gemzar is a nucleoside analog utilized as chemotherapy. It is promoted as Gemzar® by Eli Lilly and Company. Similarly as with fluorouracil and different analogs of pyrimidines, the medication replaces one of the building pieces of nucleic acids, for this circumstance cytidine, amid DNA replication. The procedure captures tumor development, as new nucleosides can't be connected to the "flawed" nucleoside, bringing about apoptosis (cell "suicide"). Gemzar is utilized as a part of different carcinomas: non-little cell lung disease, pancreatic growth, bladder tumor and bosom malignancy. It is being explored for use in oesophageal growth, and is utilized tentatively in lymphomas and different other tumor composes.

Pharmacology :

Gemzar is an antineoplastic hostile to metabolite. Hostile to metabolites take on the appearance of purine or pyrimidine - which turn into the building blocks of DNA. They keep these substances getting to be joined in to DNA amid the "S" stage (or DNA blend period of the cell cycle), ceasing typical improvement and division. Gemzar obstructs a catalyst, which changes over the cytosine nucleotide into the deoxy subsidiary. Likewise, DNA union is further repressed in light of the fact that Gemzar obstructs the fuse of the thymidine nucleotide into the DNA strand

Other Information :

Minimum Order Quantity: 1
Port of Dispatch: Mumbai
Production Capacity: 3000-4000
Delivery Time: 7-8 days.

Therapeutic Applications

Gemzar Injection is commonly used in the treatment of several types of cancers, including non-small cell lung cancer, pancreatic cancer, breast cancer, and ovarian cancer. Its effectiveness stems from its active compound, Gemcitabine Hydrochloride, which disrupts the proliferation of cancer cells, offering a targeted approach to therapy.

Preparation and Administration

Before administration, Gemzar Injection must be reconstituted with a suitable sterile diluent, such as normal saline. This process is performed by healthcare professionals in a sterile environment. The medication is given as an intravenous infusion, ensuring rapid delivery into the bloodstream for optimal therapeutic effect.

Storage and Handling

Gemzar should be stored below 30C and protected from light to maintain its efficacy. After reconstitution, the solution should be used immediately or stored as instructed by the medical provider. Single-use vials and proper handling protocols help reduce the risk of contamination.

FAQs of Gemzar Injection:

Q: How should Gemzar Injection be reconstituted and administered?

A: Gemzar Injection must be reconstituted with a suitable sterile diluent, such as normal saline (0.9% sodium chloride), by a healthcare professional. It is then administered as an intravenous infusion in a clinical setting under strict medical supervision.

Q: What are the main benefits of using Gemzar Injection?

A: Gemzar Injection delivers effective treatment against several forms of cancer by interrupting cancer cell growth. Its intravenous delivery ensures that the active ingredient, Gemcitabine Hydrochloride, rapidly enters the bloodstream for immediate therapeutic action.

Q: When is Gemzar Injection contraindicated?

A: Gemzar Injection should not be administered to individuals with known hypersensitivity to gemcitabine or any component of the formulation. Always inform your healthcare provider about any allergies or prior adverse reactions.

Q: Where should I store Gemzar Injection vials before use?

A: Gemzar Injection vials must be stored below 30C and protected from light. Proper storage preserves the medications potency and effectiveness until it is prepared for administration.

Q: What is the shelf life of Gemzar Injection, and how should unused solution be handled?

A: Gemzar Injection has a shelf life of 24 months when stored correctly. Once reconstituted, the solution should typically be used immediately. Any unused reconstituted product should be discarded according to local guidelines and healthcare facility protocols.

Q: Is a prescription required to obtain Gemzar Injection?

A: Yes, Gemzar Injection is available only by prescription. It must be administered under the supervision of a qualified healthcare provider in an appropriate medical setting.

Q: Who markets Gemzar Injection in India?

A: Gemzar Injection is marketed by Eli Lilly and Company India Pvt. Ltd., ensuring reliable quality and support for healthcare providers and patients across the market.