Doxorubicin 10 Mg/ 50 Mg Injection

Doxorubicin 10 Mg/ 50 Mg Injection Specification

Indication
Cancer Therapy (e.g., breast cancer, leukemia, lymphomas, ovarian and bladder cancer)

Salt Composition
Doxorubicin Hydrochloride

Dosage Form
Injection

Origin
Pharmaceutical

Feature
Sterile, Preservative free, Lyophilized powder or solution

Ingredients
Doxorubicin Hydrochloride, Water for Injection, Excipients

Application
Intravenous use only

Physical Color/Texture
Clear Red Solution

Fermentation Smell
Odorless

Storage Instructions
Store below 25C, Protect from light, Do not freeze

Shelf Life
24 months

Route of Administration
Intravenous (IV) infusion

Chemical Formula
C27H29NO11.HCl

Strength Available
10 mg/5 ml, 50 mg/25 ml

Reconstitution
Use Water for Injection

Compatibility
Should not be mixed with heparin or fluorouracil

ATC Code
L01DB01

Hazard
Cytotoxic agenthandle with care

Container Type
Glass vial

About Doxorubicin 10 Mg/ 50 Mg Injection

Doxorubicin 10 Mg & 50 Mg :

Doxorubicin is an anti-cancer (antineoplastic cytotoxic) chemotherapy drug. Doxorubicin is classified as an anthracycline antiobiotic.(For more detail, see How Doxorubicin Works section below).

What Doxorubicin Is Used For:

Cancers treated with Doxorubicin include: bladder, breast, head and neck, leukemia (some types), liver, lung, lymphomas, mesothelioma, multiple myeloma, neuroblastoma, ovary, pancreas, prostate, sarcomas, stomach, testis (germ cell), thyroid, uterus.

Side-Effects:

Early Side Effects: (within one week after treatment begins)

Pain along the site where the medication was given
Nausea or vomiting
Later Side Effects: (within two weeks after treatment begins)
Low blood counts. Your white and red blood cells and platelets may temporarily decrease. This can put you at increased risk for infection, anemia and/or bleeding.
Nadir: Meaning low point, nadir is the point in time between chemotherapy cycles in which you experience low blood counts.

Onset: 7 days
Nadir: 10-14 days
Recovery: 21-28 days

Mouth sores
Hair loss on the scalp or elsewhere on the body (called alopecia). Most patients do lose some or all of their hair during their treatment. But your hair will grow back after treatment is completed.

The following side effects are less common (occurring in 10-29%) for patients taking Doxorubicin:

Early: (within one week after treatment begins)

Eyes watering
Urine may appear red, red-brown, orange or pink from the color of the medication for one to two days after you receive a dose.
Later: (within two weeks after treatment begins)
Darkening of the nail beds.
Darkening of the skin where previous radiation treatment has been given.
Problems with fertility ability to bear children. (occurs in about 10% of both men and women this should be discussed with your doctor prior to therapy)

Potent Chemotherapy for Multiple Indications

Doxorubicin Injection is an established cancer therapy, utilized in diverse malignancies including breast, ovarian, bladder cancers, leukemias, and lymphomas. Its broad spectrum of action allows oncologists and healthcare professionals to employ it as a cornerstone in many chemotherapy regimens, addressing a crucial need in cancer management throughout India and globally.

Sterile and Preservative-Free Formulation

Formulated as a sterile, preservative-free solution or lyophilized powder, Doxorubicin Injection comes in glass vials for enhanced safety and purity. This ensures compatibility for intravenous use, reducing the risk of contaminants or adverse reactions, while supporting stringent pharmaceutical standards for patient safety.

Safe Handling and Storage Protocols

As a cytotoxic agent, Doxorubicin requires careful handling by medical professionals. It must be stored below 25C, protected from light, and never frozen. These measures help maintain the medicines efficacy and safety throughout its 24-month shelf life, ensuring its readiness for effective cancer treatment.

FAQs of Doxorubicin 10 Mg/ 50 Mg Injection:

Q: How should Doxorubicin Injection be administered?

A: Doxorubicin Injection is administered exclusively by intravenous (IV) infusion. A healthcare professional will prepare and infuse the solution directly into a vein. It should never be injected intramuscularly or subcutaneously.

Q: What precautions are necessary when preparing and handling this cytotoxic agent?

A: Due to its cytotoxic nature, Doxorubicin Injection must be handled with gloves, protective clothing, and in a controlled environment. Proper disposal of vials and materials is essential to prevent accidental exposure. It should not be mixed with heparin or fluorouracil to avoid incompatibilities.

Q: When is Doxorubicin Injection typically prescribed?

A: Doxorubicin is indicated for cancer therapy in conditions such as breast cancer, ovarian cancer, bladder cancer, leukemias, and lymphomas. The exact timing and dosage schedule are determined by the oncologist based on the patients condition and treatment protocol.

Q: Where should Doxorubicin Injection be stored for maximum efficacy?

A: The injection should be stored below 25C, protected from light. It must not be frozen and should remain sealed in its original glass vial packaging until use to maintain stability and effectiveness.

Q: What is the correct reconstitution process for Doxorubicin Injection?

A: For lyophilized powder forms, reconstitute Doxorubicin using only Water for Injection, as per the manufacturers instructions. Mixing with incompatible substances like heparin or fluorouracil should be avoided to ensure safe administration.

Q: What are the primary benefits of using Doxorubicin Injection in cancer therapy?

A: Doxorubicin Injection is effective against a broad range of cancers, with a proven record in improving treatment outcomes for different malignancies. Its intravenous administration provides controlled dosing and rapid action, contributing significantly to cancer management strategies.

Q: Who is authorized to use or supply Doxorubicin Injection in India?

A: Doxorubicin Injection is available for hospitals and clinics through authorized dealers, distributors, suppliers, exporters, and wholesalers in India. Only licensed healthcare professionals should administer this medication.

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