Dacarbazine Injection

Dacarbazine Injection Specification

Dosage Form
Injection

Indication
Used in the treatment of Hodgkins lymphoma, malignant melanoma, and soft tissue sarcoma

Salt Composition
Dacarbazine (Lyophilized) 200 mg/vial

Enzyme Types
Not applicable (synthetic cytotoxic agent)

Feature
Sterile, single-dose, preservative-free

Ingredients

Application
Intravenous use

Ph Level
Approximately 3 - 4 after reconstitution

Physical Color/Texture
White to off-white lyophilized powder

Fermentation Smell
Odorless or faint chemical odor

Storage Instructions
Store below 25°C, protect from light

Shelf Life
2 years

USP/Pharmacopoeial Reference
USP/Ph.Eur. standards

Reconstitution Solution
Sterile Water for Injection

Pack Size
Single vial (200 mg)

Compatibility
Compatible with 0.9% Sodium Chloride after reconstitution

Regulatory Status
Prescription only (Rx)

Disposal Instructions
Dispose of unused product and waste materials in accordance with local requirements

Packaging Type
Glass vial, sealed with rubber stopper and aluminum cap

Contraindication
Hypersensitivity to dacarbazine or any excipients

Administration Route
Intravenous infusion only

Hazard Class
Cytotoxic - handle with care

About Dacarbazine Injection

Dacarbazine Injection:-

Brand Name:	Dacarex
Contents:	Dacarbazine
International Brands:	DTIC-Dome
Manufacturer	Alkem (Cytomed)
Strength Available:	100mg / 200mg / 500mg
Packing:	Price per Vial

Efficient Management of Cancers

Dacarbazine Injection is widely used in oncology for its effectiveness against specific cancers such as Hodgkins lymphoma, malignant melanoma, and soft tissue sarcoma. Its cytotoxic action interferes with cancer cell growth and proliferation, offering promising outcomes when administered according to prescribed guidelines. The products compliance with international standards ensures reliability and safety in clinical settings.

Strict Safety and Handling Protocols

Given its classification as a cytotoxic agent, Dacarbazine Injection must be handled with caution. Healthcare professionals follow strict protocols for preparation and disposal to minimize exposure risks. The vial is single-use and preservative-free, enhancing safety and maintaining sterility during administration. Proper disposal of unused products and materials is required to conform with local regulatory policies.

Storage, Dosage, and Shelf Life Information

Dacarbazine Injection is stable for up to two years when stored below 25C and protected from light. The vial contains a white to off-white lyophilized powder to be reconstituted immediately before infusion. Strict adherence to dosage, administration, and reconstitution guidelines is vital for patient safety and effectiveness.

FAQs of Dacarbazine Injection:

Q: How should Dacarbazine Injection be prepared and administered?

A: Dacarbazine Injection must be reconstituted with Sterile Water for Injection and may be further diluted with 0.9% Sodium Chloride for intravenous infusion. The solution should be prepared aseptically and infused as directed by a healthcare professional.

Q: What are the main benefits of using Dacarbazine Injection in cancer treatment?

A: Dacarbazine Injection is highly effective in treating Hodgkins lymphoma, malignant melanoma, and soft tissue sarcoma. Its mechanism of action targets and inhibits cancer cell growth, contributing to improved patient outcomes under appropriate medical supervision.

Q: When is Dacarbazine Injection contraindicated?

A: This product is contraindicated in patients with known hypersensitivity to dacarbazine or any of its excipients. It should not be used if patients demonstrate allergic reactions to any component of the formulation.

Q: Where should Dacarbazine Injection be stored to maintain quality and safety?

A: Store the vials below 25C and protect them from light. Proper storage conditions are essential to ensure the products sterility and effectiveness until its 2-year shelf life expires.

Q: What are the disposal requirements for Dacarbazine Injection and associated materials?

A: All unused solution, vials, and medical waste must be disposed of in accordance with local regulatory guidelines for cytotoxic agents to prevent environmental contamination and accidental exposure.

Q: How is Dacarbazine Injection supplied, and who can access this medication?

A: This medication is available as a single vial containing 200 mg of lyophilized dacarbazine, distributed to licensed healthcare providers, hospitals, and authorized dealers or wholesalers. It is only available via prescription in India.

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