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Topotecan Injection

Topotecan Injection
Topotecan Injection

Topotecan Injection Specification

  • Indication
  • Treatment of ovarian cancer, small cell lung cancer, and cervical cancer
  • Dosage Form
  • Injection
  • Origin
  • Synthetic
  • Salt Composition
  • Topotecan Hydrochloride
  • Ingredients
  • Topotecan Hydrochloride, Water for Injection, Stabilizers
  • Application
  • Ph Level
  • Approximately 2.53.5
  • Physical Color/Texture
  • Clear, pale yellow solution
  • Fermentation Smell
  • Odorless
  • Storage Instructions
  • Store between 2C and 8C (Refrigerated); do not freeze
  • Shelf Life
  • 24 months
  • Availability
  • Prescription only
  • Administration Route
  • Intravenous infusion
  • Compatibility
  • Compatible with 0.9% Sodium Chloride and 5% Dextrose solutions
  • Packaging Type
  • Glass vial
  • Strength
  • 2.5 mg/1 ml
  • USP/Standards
  • Meets pharmacopeial standards
  • Precautions
  • For hospital use only; administration under physician supervision
  • pH Adjuster
  • Hydrochloric acid and/or sodium hydroxide (for pH adjustment)
 
 

About Topotecan Injection

Topotecan:-

Topotecan is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. This medication is classified as an topoisomerase 1 inhibitor. Hycamtin.

Topotecan may be given as a drip (infusion) in one of the following ways:

  • by injection into a vein (intravenously), through a fine tube inserted into a vein, usually in the back of your hand (cannula)
  • through a fine, plastic tube inserted under the skin and into a vein near your collarbone (central line)
  • into a fine tube inserted into a vein in the crook of your arm (PICC line).

The infusion takes approximately 30 minutes. Topotecan can also be taken as capsules that should be swallowed whole with a glass of water. The capsules can be taken with or without food. Your doctor may want you to take a combination of 0.25mg and 1mg capsules. You need to make sure you're taking the right dose and that you don't take too much or too little.

 



Reliable Chemotherapy Solution

Topotecan Injection delivers reliable and targeted chemotherapy for patients with select cancers, including ovarian, small cell lung, and cervical cancers. Adhering to strict USP standards, it combines efficacy and patient safety. Formulated as a clear, pale yellow solution, its precise composition ensures consistent performance and compatibility during intravenous administration.


Specialized Hospital Administration

Designed strictly for hospital use, Topotecan Injection is administered under the close supervision of oncology specialists. This ensures correct dosing, monitoring of patient response, and management of any infusion-related reactions. Only trained healthcare professionals in certified facilities should handle and dispense this medication.

FAQs of Topotecan Injection:


Q: How should Topotecan Injection be administered to patients?

A: Topotecan Injection must be given as an intravenous infusion by a healthcare professional in a hospital setting. It is not intended for self-administration or use outside of medical supervision.

Q: What are the indications for using Topotecan Injection?

A: This medication is indicated for the treatment of ovarian cancer, small cell lung cancer, and cervical cancer as part of an anticancer chemotherapy regimen.

Q: When should Topotecan Injection not be used?

A: Topotecan Injection should not be used without a doctors prescription or outside of a hospital. It is unsuitable for patients with known hypersensitivity to any of its components. Administration during pregnancy or in individuals with severe bone marrow suppression should be avoided without thorough medical evaluation.

Q: Where should Topotecan Injection be stored before use?

A: The injection should be stored refrigerated between 2C and 8C and should not be frozen. Proper storage preserves its efficacy and safety profile over its 24-month shelf life.

Q: What is the process for preparing Topotecan Injection for infusion?

A: Before infusion, Topotecan Injection must be diluted using either 0.9% Sodium Chloride or 5% Dextrose solution. Only qualified medical personnel should handle preparation and administration, following sterile techniques.

Q: How does Topotecan Injection benefit patients with cancer?

A: As an anticancer agent, Topotecan targets and inhibits cancer cell replication, helping to control and reduce tumor growth in patients with specified cancers.

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