PEG Grafeel Injection

PEG Grafeel Injection Specification

Salt Composition
Pegfilgrastim (Filgrastim Pegylated)

Indication
Reduction in the duration of neutropenia and the incidence of febrile neutropenia in patients treated with cytotoxic chemotherapy

Dosage Form
Injection

Origin
India

Ingredients
Pegfilgrastim

Application

Physical Color/Texture
Clear, colorless solution

Fermentation Smell
Odorless

Enzymatic Activity
Stimulates proliferation and differentiation of neutrophil progenitor cells

Storage Instructions
Store in a refrigerator (2C 8C); do not freeze

Shelf Life
24 months from date of manufacture

Administration Route
Subcutaneous injection

Drug Class
Colony Stimulating Factors

Contraindications
Known hypersensitivity to pegfilgrastim or any of its components

Prescription Status
Prescription only (Rx)

Common Side Effects
Bone pain, myalgia, headache, injection site reactions

Molecular Weight
Approximately 39 kDa

About PEG Grafeel Injection

PEG Grafeel : Dr Reddy Laboratories launched Peg-grafeel, Dr Reddy brand of pegfilgrastim in India. Peg-grafeel has been approved in India to reduce the duration of neutropenia and the incidence of febrile neutropenia in patients treated with cytotoxic chemotherapy for malignancy with the exception of chronic myeloid leukaemia and myelodysplastic syndromes.

Pegfilgrastim is a pegylated long-lasting variant of filgrastim. One injection of pegfilgrastim can replace up to 14 injections of filgrastim, which must be administered daily. It can be administered once per chemotherapy cycle, providing convenience to the patient while eliminating many of the additional costs of treatment.

Peg-grafeel is priced at an MRP of Rs.8,865 and represents a breakthrough in the pricing of this complex molecule. It is priced at approximately 25 per cent of the originator brand in India, and is priced 95 per cent lower than the US price for pegfilgrastim.

Peg-grafeel 6mg (pegfilgrastim), a doctor prescribed medication is utilized to diminish the length of neutropenia and the occurrence of febrile neutropenia in patients treated with cytotoxic chemotherapy for danger (except for interminable myeloid leukemia and myelodysplastic disorders). Peg-grafeel injection is utilized to anticipate contaminations after chemotherapy.

Produced : dr reddy's laboratories ltd

Additional information :

Dosages available : 6mg injection
Capacity : Store at 2^oC-8^oC . Try not to refrigerate
Dosages : 6mg subcutaneous once per chemotherapy cycle. Try not to manage in the period 14 days before and 24 hours after administrator of cytotoxic chemotherapy.

Indications :

Most normal reactions might be bone torment, headache, swelling in the arms or legs, obstruction, drinking more fluids, working out, or adding fiber to your eating routine may help.
Pack size: pack of 1 vial

How Does PEG Grafeel Injection Work?

PEG Grafeel Injection contains pegfilgrastim, which stimulates the bone marrow to produce more neutrophils. As a colony stimulating factor, it enhances the proliferation and differentiation of neutrophil progenitor cells, supporting the immune system during chemotherapy and lowering the risk of infections.

Administration and Storage Guidelines

PEG Grafeel Injection is administered subcutaneously by a healthcare professional. It should be stored in a refrigerator at 2C8C and should not be frozen. Adhering to these storage instructions is essential for maintaining the effectiveness and safety of the medication.

Who Should Not Use PEG Grafeel?

Individuals with known hypersensitivity to pegfilgrastim or any component of the injection should not use PEG Grafeel. If you have a history of allergies to similar drugs, consult your healthcare provider before considering this medication.

FAQs of PEG Grafeel Injection:

Q: What is the primary benefit of using PEG Grafeel Injection during chemotherapy?

A: PEG Grafeel Injection reduces the duration of neutropenia and helps lower the risk of febrile neutropenia and related infections in patients receiving cytotoxic chemotherapy, thus supporting overall immune health.

Q: How should PEG Grafeel Injection be administered?

A: PEG Grafeel Injection is given as a subcutaneous injection, usually by a healthcare professional. It is important to follow your doctors instructions regarding dosage and schedule.

Q: When should PEG Grafeel be used in the course of chemotherapy?

A: PEG Grafeel is typically administered once per chemotherapy cycle, following your healthcare providers guidance. The timing depends on the specific chemotherapy regimen and individual patient needs.

Q: Where should I store the PEG Grafeel Injection?

A: Store PEG Grafeel in a refrigerator at 2C8C. Do not freeze the medication and ensure it is protected from light. Always keep it out of reach of children.

Q: What are common side effects of PEG Grafeel Injection?

A: Frequently reported side effects include bone pain, myalgia, headache, and injection site reactions. If you experience any severe allergic reactions, seek immediate medical attention.

Q: Who should not receive PEG Grafeel Injection?

A: PEG Grafeel should not be given to anyone with known hypersensitivity to pegfilgrastim or any of its components. Inform your healthcare provider of all allergies before starting the medication.

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