Dactinomycin injection

Dactinomycin injection Specification

Origin
Synthetic

Salt Composition
Dactinomycin (also known as Actinomycin D)

Dosage Form
Injection

Ingredients
Dactinomycin with suitable excipients for injection

Application
Intravenous administration in oncology

Fermentation Smell
Odorless

Storage Instructions
Store below 25°C, protect from light; store reconstituted solutions at 2°C to 8°C for up to 24 hours

Shelf Life
24 months (unopened)

Disposal
Dispose of unused product and waste materials as per cytotoxic waste guidelines

Regulatory Status
Prescription drug; Rx only; subject to cytotoxic guidelines

Pregnancy Category
Category D

Brand Name
Varies by manufacturer (e.g., Cosmegen)

Strength
500 mcg (0.5 mg) per vial

Preservatives
No preservatives

Route of Administration
Intravenous (IV) only

Reconstitution
Reconstitute with sterile water for injection

Dactinomycin injection Trade Information

Supply Ability
100 Bottles Per Week

Delivery Time
1 Week

About Dactinomycin injection

Dactnomycin:-

Dactinomycin is used to treat Wilms and Ewings tumors, testicular cancer, sarcomas (cancers that grow from cartilage, fat, muscle, or bone), and other types of cancer.

Dactinomycin is used in combination with other medications, surgery, and/or radiation therapy to treat Wilms' tumor (a type of kidney cancer that occurs in children) and rhabdomyosarcoma (cancer that forms in muscles) in children. Dactinomycin is also used in combination with other medications to treat certain types of testicular cancer and Ewing's sarcoma (a type of cancer in bones or muscles). Dactinomycin is also used alone or in combination with other medications to treat gestational trophoblastic tumors (a type of tumor that forms inside a woman's uterus while she is pregnant). Dactinomycin may also be used to treat certain types of cancerous tumors that are located in a specific area of the body. Dactinomycin is a type of antibiotic that is only used in cancer chemotherapy. It works by slowing or stopping the growth of cancer cells in your body

Dactinomycin comes as a powder to be mixed with liquid to be injected intravenously (into a vein) by a doctor or nurse in a medical facility. The length of treatment depends on the type of cancer you have, the types of other drugs you are taking, and how well your body responds to treatment. Your doctor may need to stop or delay your treatment if you experience certain side effects. Dactinomycin may also be injected by a doctor directly into a specific the part of the body or the organ to treat the area where a tumor is located.

Powerful Oncology Application

Dactinomycin injection is extensively utilized in the treatment of certain cancers, including those affecting children and adults. The medications proven efficacy in oncology arises from its ability to interfere with cancer cell replication. Administered intravenously, it forms a crucial part of multi-drug chemotherapy regimens, helping improve patient outcomes under professional supervision.

Safe Handling and Prescription Use

As a cytotoxic agent, Dactinomycin injection requires careful handling and is only available by prescription. Healthcare professionals must follow established safety protocols during preparation, administration, and disposal to avoid accidental exposure. The product contains no preservatives, and all waste should be managed according to cytotoxic guidelines to ensure the safety of medical staff and the environment.

FAQs of Dactinomycin injection:

Q: How should Dactinomycin injection be prepared and administered?

A: Dactinomycin injection must be reconstituted with sterile water for injection before use. It is administered intravenously (IV) only, by a healthcare professional experienced in cytotoxic therapies.

Q: What are the storage requirements for Dactinomycin injection and its reconstituted solution?

A: Unopened vials should be stored below 25C and protected from light. After reconstitution, the solution must be stored at 2C to 8C and used within 24 hours.

Q: When is Dactinomycin injection prescribed and who can administer it?

A: This medication is prescribed specifically for oncology indications and must be administered by qualified healthcare professionals in a clinical setting. It is not for self-administration.

Q: Where can Dactinomycin injection be disposed of safely?

A: Unused product, reconstituted solution, and associated waste must be disposed of following cytotoxic waste handling guidelines to ensure safety and regulatory compliance.

Q: What benefits does Dactinomycin injection provide in cancer therapy?

A: Dactinomycin injection inhibits cancer cell proliferation, making it a valuable component in various chemotherapy regimens, contributing to improved treatment outcomes in oncology.

Q: Is Dactinomycin injection safe for use during pregnancy?

A: Dactinomycin is classified as Pregnancy Category D, indicating a known risk; it should only be used in pregnant women when clearly needed and prescribed by an oncology specialist.