Buminate - Human Albumin

Buminate - Human Albumin Specification

Indication
Restoration and maintenance of circulating blood volume

Salt Composition
Human Albumin IP 20% (20g/100mL)

Dosage Form
Infusion (Injection Solution)

Enzyme Types
Not applicable (Human protein)

Feature
Sterile, pyrogen-free, ready-to-use, high purity

Ingredients
Human Albumin, Sodium Caprylate, N-acetyltryptophanate, Sodium Chloride, Water for Injection

Application
Hypovolemia, burns, shock, hypoalbuminemia, acute liver failure, cardiopulmonary bypass, hemodialysis, and therapeutic plasma exchange

Ph Level
6.77.3

Physical Color/Texture
Clear, yellowish liquid

Fermentation Smell
Odorless

Storage Instructions
Store below 25C. Do not freeze.

Shelf Life
3 years

About Buminate - Human Albumin

Buminate - Human Albumin:-

Albumin solution human is used to increase blood volume and to replace the volume of blood that has been lost from the body.

Albumin is also indicated in the emergency treatment of shock and in other similar conditions where the restoration of blood volume is urgent. If there has been considerable loss of red blood cells, transfusion with packed red blood cells is indicated.

Albumin or Albumin in either normal saline or dextrose is indicated to prevent marked hemoconcentration and to maintain appropriate electrolyte balance.

Albumin is indicated in those clinical situations usually associated with a low concentration of plasma protein and a resulting decreased circulating blood volume. Although diuresis may occur soon after albumin administration has been instituted, best results are obtained if albumin is continued until the normal serum protein level is regained.

Ready-to-Use High Purity Albumin

Buminate is supplied as a clear, yellowish, ready-to-use solution, ensuring high purity and sterility for safe intravenous infusion. Designed for immediate clinical situations, it meets the demanding needs of hospitals and healthcare providers seeking reliable support for blood volume restoration.

Versatile Clinical Applications

Applicable for various life-threatening conditions such as hypovolemia, burns, shock, and acute liver failure, Buminate provides essential volume expansion and protein replacement. Its use is critical during procedures like cardiopulmonary bypass and therapeutic plasma exchange, making it indispensable in intensive care units.

Precise Manufacturing Standards

Manufactured by Baxter Healthcare, Buminate adheres to stringent quality standards. The solution is pyrogen-free and maintained at a pH of 6.77.3, ensuring compatibility and safety. It is distributed through dealers, exporters, and wholesalers across India, allowing broad clinical access.

FAQs of Buminate - Human Albumin:

Q: How is Buminate administered to patients?

A: Buminate is administered intravenously by healthcare professionals. The dosage and infusion rate are tailored to individual patient needs, taking into account their condition and response to treatment.

Q: What conditions is Buminate indicated for?

A: Buminate is indicated for restoration and maintenance of circulating blood volume loss in cases such as hypovolemia, burns, shock, hypoalbuminemia, acute liver failure, cardiopulmonary bypass, hemodialysis, and therapeutic plasma exchange.

Q: When should Buminate not be used?

A: Buminate is contraindicated in patients with severe anemia, cardiac failure, or known intolerance to human albumin. Its use should be carefully evaluated in these situations.

Q: Where should Buminate be stored to ensure stability?

A: Buminate should be stored below 25C and should not be frozen. Proper storage preserves its sterility and three-year shelf life.

Q: What are the primary benefits of using Buminate?

A: Buminate provides rapid and effective expansion of blood volume and protein replacement in critical care. Its high purity and ready-to-use formulation offer consistent clinical outcomes in emergency and elective settings.

Q: What precautions should be taken during Buminate administration?

A: Careful monitoring for signs of volume overload is important, especially in patients with cardiac or renal impairment. Appropriate dosing and slow infusion rates can help mitigate potential complications.

Q: What is the composition of Buminate and what makes it unique?

A: Buminate contains 20% human albumin along with sodium caprylate, N-acetyltryptophanate, sodium chloride, and water for injection. Its sterile, pyrogen-free, high-purity formulation sets it apart for reliable intravenous infusion therapy.

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